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KMID : 1011420180230040365
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Journal of Korean Ophthalmic Optics Society
2018 Volume.23 No. 4 p.365 ~ p.377
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The Effect of Non-compliant Use of an Eyewash Solution on Lens Parameters and Pigmentation of Circle Soft Contact Lenses
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Kim Ji-Hye
Park Min-Hye
Yoo Do-Yeon
Shin Jang-Cheol
Park Mi-Jung
Kim So-Ra
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Abstract
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Purpose: In the present study, the effect of exposure to eyewash solution on lens parameters and dye elution of circle soft contact lenses (hereafter circle lenses) was investigated. The restoration of circle lens parameters changed by exposure to eyewash solution was also tested.
Methods: Four hydrogel circle lenses (etafilcon A, hilafilcon B, nelfilcon A, and polymacon) and a silicone hydrogel circle lens (lotrafilcon B) were selected and exposed to an eyewash solution for 1, 2, 4, and 8 hours. The change of lens parameters was confirmed by measuring refractive power, central thickness, total diameter, radius of curvature, water content, and visible light transmission of each lens before and after the exposure to eyewash solution. Dye elution was investigated using a cotton swab rubbing test and observation through scanning electron microscopy (SEM).
Results: The refractive error of etafilcon A and nelfilcon A circle lenses, high water content hydrogel lenses, significantly increased, and their total diameter, base curvature, and water content significantly decreased after exposure to the eyewash solution; however, the pattern of change with respect to exposure time was different according to the ionicity of lens materials. On the other hand, central thickness and total diameter of the hilafilcon B circle lens, high water and non-ionic lens, increased until 1 hour-exposure time. The lens parameters of polymacon (low water and non-ionic hydrogel) and lotrafilcon B (silicone hydrogel) were not significantly affected by the eyewash solution. The change in parameters of those circle lenses as a result of exposure to eyewash solution were restored after 1-hour treatment with multi-purpose solution (MPS), indicating that there was no statistically significant difference between the levels before eyewash solution exposure for all circle lenses. After 8-hour treatment in MPS, it was confirmed that the lens parameters were recovered to within the allowable range of error provided by Korea Food and Drug Administration (KFDA) except for nelfilcon A circle lens. Dye elution was observed in the hilafilcon B, polymacon and lotrafilcon B circle lenses before and after exposure to the eyewash solution as assessed using the cotton swab rubbing test, and surface damage was observed using SEM after 8 hour-exposure to eyewash solution.
Conclusions: From the results of this study, it was revealed that the change over time and pattern of lens parameters in high water circle lenses varied based on ionicity when exposed to eyewash solution, and these changes were all restored to within the allowable range of error provided by KFDA when further treated with MPS. Dye elution and surface damage of the circle lenses were observed in non-ionic low water hydrogel and silicone hydrogel lens exhibited no parameter change. Therefore, it is expected that repeated rubbing and/or wearing circle lenses that have induced change of lens parameter or possibility of dye elution due to surface damage after exposure to eyewash solution will affect not only the fit of the lens but also eye health.
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KEYWORD
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Eyewash solution, Circle soft contact lens, Hydrogel lens, Silicone hydrogel lens, Lens parameter, Lens surface, Dye elution
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